An estimated 85% of efforts in biomedical research are wasted due to inefficiencies. This wastage represents a global financial loss of greater than US$200 billion per year, a barrier to practicing evidence-based medicine, and a considerable amount of carbon emission. Inefficiencies exist throughout the research lifecycle, from strategic planning, design, execution, reporting, and publication. Medical writers and communicators are well-positioned to help prevent research waste and mitigate adverse effects on planetary health through actions related to good research practice, data stewardship, responsible reporting, and open science