Medical communicators can choose words that influence how people perceive individuals and populations who take part in research. For many years, the term subjects was used ubiquitously and internationally in clinical research. However, this term can fuel disrespect, mistrust, and bias in clinical practice and research. As a result, subjects has been increasingly replaced with the more precise and respectful term participants. However, other terms may more accurately and precisely describe people who take part in clinical research while also recognising their contributions, autonomy, humanity, and individuality with respect, empathy, compassion, and kindness.  Medical Writing. 2025;34(2):66–68. https://doi.org/10.56012/wakl7985