Systematic literature reviews are an essential component of the medical device clinical evaluation process. The EU Medical Device Regulation requirement for regularly updated systematic literature searches will increase the burden on the medical writer to maintain and update systematic reviews for many systems and devices. Specialists in systematic reviews are beginning to adopt artificial intelligence tools that aim to optimise searches and streamline the review process. As these tools mature, the medical device writer tasked with a systematic review may want to consider the potential benefits of integrating them into their established systematic review process.