Remote working is the new normal since the COVID-19 pandemic, so learning to lead a virtual team successfully is now an essential core competency for organisational leaders. The transition from co-located teams to virtual teams has benefitted leaders by facilitating hiring of diverse talent from different geographical locations and led to increased employee contentment due to flexible working hours, increased autonomy, and freedom to relocate. However, leading virtual teams creates challenges for leaders, such as employee engagement in the absence of face-to-face conversations, workplace isolation, and team cohesion. Overcoming these challenges will be crucial for leaders to be successful in the future. This article presents an overview of the advantages, challenges, and approaches to overcome the challenges in the virtual environment.   Medical Writing. 2022;31(3)50-53. https://doi.org/10.56012/njdd3467